Anti-SLC24A2 Antibody

Sodium/potassium/calcium exchanger 2; Na (+) /K (+) /Ca (2+) -exchange protein 2; Retinal cone Na-Ca+K exchanger; Solute carrier family 24 member 2; SLC24A2; NCKX2;

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca (2+) and 1 K (+) in exchange for 4 Na (+) .