Anti-ARHGAP44 Antibody
Boster Bio Anti-ARHGAP44 Antibody catalog # A11389. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Rho GTPase-activating protein 44; NPC-A-10; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; RICH-2; ARHGAP44; KIAA0672, RICH2;
Gene Name
ARHGAP44
UniProt
Q17R89
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ARHGAP44 (NP_055674.4) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain. Expressed at weak level in other tissues.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP- bound states. May act as a GAP for CDC42 and RAC1. Endosomal recycling protein which, in association with SHANK3, is involved in synaptic plasticity. Promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation.
Molecular Weight
89247 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Rho GTPase-activating protein 44
Subcellular Location
Cell projection, dendritic spine . Recycling endosome . Cell junction, synapse . In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites. .
Protein Name
Rho GTPase-activating protein 44
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