Anti-C-myc promoter-binding protein DENND4A Antibody
Boster Bio Anti-C-myc promoter-binding protein DENND4A Antibody catalog # A11173. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
C-myc promoter-binding protein; DENN domain-containing protein 4A; DENND4A; IRLB, MYCPBP;
Gene Name
DENND4A
UniProt
Q7Z401
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human DENND4A (NP_005839.3) .
Clonality
Polyclonal
Tissue Specificity
Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
Molecular Weight
209244 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
C-myc promoter-binding protein
Subcellular Location
Nucleus .
Protein Name
C-myc promoter-binding protein
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