Anti-INPP5K Antibody
Boster Bio Anti-INPP5K Antibody catalog # A11107. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Inositol polyphosphate 5-phosphatase K ;3.1.3.56
Gene Name
INPP5K
UniProt
Q9BT40
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human INPP5K (NP_057616.2) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate (PubMed:10753883) . Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle (By similarity) .
Molecular Weight
51090 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Inositol polyphosphate 5-phosphatase K
Subcellular Location
Endoplasmic reticulum
Protein Name
Inositol polyphosphate 5-phosphatase K
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