Anti-COMMD5 Antibody
Boster Bio Anti-COMMD5 Antibody catalog # A10717. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
COMM domain-containing protein 5; Hypertension-related calcium-regulated gene protein; HCaRG; COMMD5; HT002;
Gene Name
COMMD5
UniProt
Q9GZQ3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human COMMD5 (NP_054785.2) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237) . Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity) . Down-regulates activation of NF-kappa-B (PubMed:15799966) .
Molecular Weight
24670 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
COMM domain-containing protein 5
Subcellular Location
Cytoplasm
Protein Name
COMM domain-containing protein 5
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