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Anti-COMMD5 Antibody

Boster Bio Anti-COMMD5 Antibody catalog # A10717. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

COMM domain-containing protein 5; Hypertension-related calcium-regulated gene protein; HCaRG; COMMD5; HT002;

Gene Name

COMMD5

UniProt

Q9GZQ3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human COMMD5 (NP_054785.2) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver.

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237) . Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity) . Down-regulates activation of NF-kappa-B (PubMed:15799966) .

Molecular Weight

24670 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

COMM domain-containing protein 5

Subcellular Location

Cytoplasm

Protein Name

COMM domain-containing protein 5

Frequently Asked Questions

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