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Anti-Centromere protein K CENPK Antibody

Boster Bio Anti-Centromere protein K CENPK Antibody catalog # A10647. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Centromere protein K; CENP-K; Interphase centromere complex protein 37; Protein AF-5alpha; p33; CENPK; ICEN37; FKSG14;

Gene Name

CENPK

UniProt

Q9BS16

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein of human CENPK (NP_071428.2) .

Clonality

Polyclonal

Tissue Specificity

Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.

Molecular Weight

31655 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10647

Product MSDS

https://www.bosterbio.com/msds?sku=A10647

Other Gene Names

Centromere protein K

Subcellular Location

Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.

Protein Name

Centromere protein K

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