Anti-Centromere protein K CENPK Antibody
Boster Bio Anti-Centromere protein K CENPK Antibody catalog # A10647. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Centromere protein K; CENP-K; Interphase centromere complex protein 37; Protein AF-5alpha; p33; CENPK; ICEN37; FKSG14;
Gene Name
CENPK
UniProt
Q9BS16
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human CENPK (NP_071428.2) .
Clonality
Polyclonal
Tissue Specificity
Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
Molecular Weight
31655 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Centromere protein K
Subcellular Location
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein Name
Centromere protein K
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