Anti-STAC3 Antibody
Boster Bio Anti-STAC3 Antibody catalog # A10496. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
SH3 and cysteine-rich domain-containing protein 3; STAC3;
Gene Name
STAC3
UniProt
Q96MF2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human STAC3
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca (2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels (PubMed:23736855, PubMed:29078335) . Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (By similarity) . Slows down the inactivation rate of the calcium channel CACNA1C (in vitro) (PubMed:29078335) .
Molecular Weight
41507 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
SH3 and cysteine-rich domain-containing protein 3
Subcellular Location
Cytoplasm
Protein Name
SH3 and cysteine-rich domain-containing protein 3
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