Anti-UBASH3A Antibody
Boster Bio Anti-UBASH3A Antibody catalog # A10433. Tested in WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ubiquitin-associated and SH3 domain-containing protein A; Cbl-interacting protein 4; CLIP4; Suppressor of T-cell receptor signaling 2; STS-2; T-cell ubiquitin ligand 1; TULA-1; UBASH3A; STS2;
Gene Name
UBASH3A
UniProt
P57075
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 356-401 of Human UBASH3A.
Clonality
Polyclonal
Applications
WB, ICC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Molecular Weight
74123 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ubiquitin-associated and SH3 domain-containing protein A
Subcellular Location
Cytoplasm. Nucleus.
Protein Name
Ubiquitin-associated and SH3 domain-containing protein A
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