Anti-MAPKBP1 Antibody
Boster Bio Anti-MAPKBP1 Antibody catalog # A10423. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Mitogen-activated protein kinase-binding protein 1; JNK-binding protein 1; JNKBP-1; MAPKBP1; JNKBP1, KIAA0596;
Gene Name
MAPKBP1
UniProt
O60336
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human MAPKBP1 (NP_001122080.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes (PubMed:22700971) . Expressed in kidney (PubMed:28089251) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response (PubMed:22700971) . Involved in JNK signaling pathway (By similarity) .
Molecular Weight
163818 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Mitogen-activated protein kinase-binding protein 1
Subcellular Location
Cytoplasm
Protein Name
Mitogen-activated protein kinase-binding protein 1
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