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Anti-SLC24A1 Antibody

Boster Bio Anti-SLC24A1 Antibody catalog # A10359. Tested in WB, ICC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Sodium/potassium/calcium exchanger 1; Na (+) /K (+) /Ca (2+) -exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1; SLC24A1; KIAA0702, NCKX1;

Gene Name

SLC24A1

UniProt

O60721

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 198-243 of Human SLC24A1.

Clonality

Polyclonal

Tissue Specificity

Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer.

Applications

WB, ICC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca (2+) and 1 K (+) in exchange for 4 Na (+) .

Molecular Weight

121374 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Sodium/potassium/calcium exchanger 1

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

Sodium/potassium/calcium exchanger 1

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