Anti-ASCC3 Antibody
Boster Bio Anti-ASCC3 Antibody catalog # A10007. Tested in ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Activating signal cointegrator 1 complex subunit 3;3.6.4.12
Gene Name
ASCC3
UniProt
Q8N3C0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ASCC3 (NP_071374.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
ICC/IF: 1:50-1:100
Form
Liquid
Function
3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions (PubMed:22055184) . Part of the ASC-1 complex that enhances NF- kappa-B, SRF and AP1 transactivation (PubMed:12077347) .
Molecular Weight
251460 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Activating signal cointegrator 1 complex subunit 3
Subcellular Location
Nucleus
Protein Name
Activating signal cointegrator 1 complex subunit 3
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