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Anti-THO complex subunit 7 homolog THOC7 Antibody

Boster Bio Anti-THO complex subunit 7 homolog THOC7 Antibody catalog # A10001. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

THO complex subunit 7 homolog; Functional spliceosome-associated protein 24; fSAP24; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1-binding protein 1; hTREX30; THOC7; NIF3L1BP1;

Gene Name

THOC7

UniProt

Q6I9Y2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human THOC7 (NP_079351.2) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

Molecular Weight

23743 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10001

Product MSDS

https://www.bosterbio.com/msds?sku=A10001

Other Gene Names

THO complex subunit 7 homolog

Subcellular Location

Cytoplasm

Protein Name

THO complex subunit 7 homolog

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