Anti-THO complex subunit 7 homolog THOC7 Antibody
Boster Bio Anti-THO complex subunit 7 homolog THOC7 Antibody catalog # A10001. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
THO complex subunit 7 homolog; Functional spliceosome-associated protein 24; fSAP24; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1-binding protein 1; hTREX30; THOC7; NIF3L1BP1;
Gene Name
THOC7
UniProt
Q6I9Y2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human THOC7 (NP_079351.2) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.
Molecular Weight
23743 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A10001
Product MSDS
https://www.bosterbio.com/msds?sku=A10001
Other Gene Names
THO complex subunit 7 homolog
Subcellular Location
Cytoplasm
Protein Name
THO complex subunit 7 homolog
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