Anti-Barttin BSND Antibody

Boster Bio Anti-Barttin BSND Antibody catalog # A09766. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Barttin; BSND; BART;

Gene Name

BSND

UniProt

Q8WZ55

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human BSND (NP_476517.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.

Molecular Weight

35197 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Barttin

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cytoplasm . A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity) . .