Anti-Barttin BSND Antibody
Boster Bio Anti-Barttin BSND Antibody catalog # A09766. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Barttin; BSND; BART;
Gene Name
BSND
UniProt
Q8WZ55
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human BSND (NP_476517.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
Molecular Weight
35197 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Barttin
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Cytoplasm . A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity) . .
Protein Name
Barttin
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