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Anti-NEK3 Antibody

Boster Bio Anti-NEK3 Antibody catalog # A09729. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Serine/threonine-protein kinase Nek3;2.7.11.1; HSPK 36; Never in mitosis A-related kinase 3; NimA-related protein kinase 3; NEK3;

Gene Name

NEK3

UniProt

P51956

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human NEK3 (NP_689933.1) .

Clonality

Polyclonal

Tissue Specificity

Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2. Implicated in prolactin- mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.

Molecular Weight

57705 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Serine/threonine-protein kinase Nek3

Subcellular Location

Cytoplasm . Cell projection, axon .

Protein Name

Serine/threonine-protein kinase Nek3

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