Anti-TBC1 domain family member 2A TBC1D2 Antibody
Boster Bio Anti-TBC1 domain family member 2A TBC1D2 Antibody catalog # A09458. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
TBC1 domain family member 2A; Armus; Prostate antigen recognized and identified by SEREX 1; PARIS-1; TBC1D2; PARIS1, PP8997, TBC1D2A;
Gene Name
TBC1D2
UniProt
Q9BYX2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human TBC1D2.
Clonality
Polyclonal
Tissue Specificity
Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
Molecular Weight
105414 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
TBC1 domain family member 2A
Subcellular Location
Cytoplasm
Protein Name
TBC1 domain family member 2A
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