Anti-MEX3C Antibody
Boster Bio Anti-MEX3C Antibody catalog # A09281-1. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
RNA-binding E3 ubiquitin-protein ligase MEX3C;2.3.2.27; RING finger and KH domain-containing protein 2; RING finger protein 194; RING-type E3 ubiquitin transferase MEX3C ; MEX3C; RKHD2, RNF194; BM-013;
Gene Name
MEX3C
UniProt
Q5U5Q3
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human MEX3C (NP_057710.3) .
Clonality
Polyclonal
Tissue Specificity
Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Highly expressed in cells of the innate immune system, in particular activated NK cells. Week expression in the intestine.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
E3 ubiquitin ligase responsible for the post- transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
Molecular Weight
69366 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A09281-1
Product MSDS
https://www.bosterbio.com/msds?sku=A09281-1
Other Gene Names
RNA-binding E3 ubiquitin-protein ligase MEX3C
Subcellular Location
Cytoplasm
Protein Name
RNA-binding E3 ubiquitin-protein ligase MEX3C
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