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Anti-MEX3C Antibody

Boster Bio Anti-MEX3C Antibody catalog # A09281-1. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

RNA-binding E3 ubiquitin-protein ligase MEX3C;2.3.2.27; RING finger and KH domain-containing protein 2; RING finger protein 194; RING-type E3 ubiquitin transferase MEX3C ; MEX3C; RKHD2, RNF194; BM-013;

Gene Name

MEX3C

UniProt

Q5U5Q3

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein of human MEX3C (NP_057710.3) .

Clonality

Polyclonal

Tissue Specificity

Highest levels found in fetal brain and testis. Also expressed in thymus, salivary gland and uterus. Highly expressed in cells of the innate immune system, in particular activated NK cells. Week expression in the intestine.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

E3 ubiquitin ligase responsible for the post- transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.

Molecular Weight

69366 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

RNA-binding E3 ubiquitin-protein ligase MEX3C

Subcellular Location

Cytoplasm

Protein Name

RNA-binding E3 ubiquitin-protein ligase MEX3C

Frequently Asked Questions

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