What is the catalog number for Anti-CIAO1 Antibody?

The catalog number for Anti-CIAO1 Antibody is A09213.

What sizes are available for Anti-CIAO1 Antibody?

Anti-CIAO1 Antibody is available in the following size(s): 100 µL.

Is Anti-CIAO1 Antibody in stock?

Anti-CIAO1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CIAO1 Antibody?

The safety data sheet for Anti-CIAO1 Antibody is available here: https://www.bosterbio.com/msds?sku=A09213.

Anti-CIAO1 Antibody

Boster Bio Anti-CIAO1 Antibody catalog # A09213. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Probable cytosolic iron-sulfur protein assembly protein CIAO1

Gene Name

CIAO1

UniProt

O76071

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human CIAO1.

Clonality

Polyclonal

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:17937914, PubMed:23891004) . As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (PubMed:23891004) . Seems to specifically modulate the transactivation activity of WT1 (PubMed:9556563) . As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (PubMed:20797633) .