Anti-RNF135 Antibody
Boster Bio Anti-RNF135 Antibody catalog # A09212. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
E3 ubiquitin-protein ligase RNF135;2.3.2.27; RIG-I E3 ubiquitin ligase; REUL; RING finger protein 135; RING-type E3 ubiquitin transferase RNF135 ; Riplet; RNF135; L13;
Gene Name
RNF135
UniProt
Q8IUD6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human RNF135.
Clonality
Polyclonal
Tissue Specificity
Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.
Molecular Weight
47888 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
E3 ubiquitin-protein ligase RNF135
Subcellular Location
Cytoplasm
Protein Name
E3 ubiquitin-protein ligase RNF135
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