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Anti-RNF135 Antibody

Boster Bio Anti-RNF135 Antibody catalog # A09212. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase RNF135;2.3.2.27; RIG-I E3 ubiquitin ligase; REUL; RING finger protein 135; RING-type E3 ubiquitin transferase RNF135 ; Riplet; RNF135; L13;

Gene Name

RNF135

UniProt

Q8IUD6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human RNF135.

Clonality

Polyclonal

Tissue Specificity

Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.

Molecular Weight

47888 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A09212

Product MSDS

https://www.bosterbio.com/msds?sku=A09212

Other Gene Names

E3 ubiquitin-protein ligase RNF135

Subcellular Location

Cytoplasm

Protein Name

E3 ubiquitin-protein ligase RNF135

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