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Anti-ALKBH4 Antibody

Boster Bio Anti-ALKBH4 Antibody catalog # A09200. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4;1.14.11.-; Alkylated DNA repair protein alkB homolog 4; ALKBH4; ABH4;

Gene Name

ALKBH4

UniProt

Q9NXW9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human ALKBH4 (NP_060091.1) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with highest expression in pancreas, ovary and spleen.

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

Molecular Weight

33838 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

Subcellular Location

Cytoplasm. Nucleus. Midbody. Associates with the contractile ring and midbody.

Protein Name

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

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