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Anti-NY-CO-1 (K914) NEMF Antibody

Boster Bio Anti-NY-CO-1 (K914) NEMF Antibody catalog # A09039-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1; NEMF; SDCCAG1;

Gene Name

NEMF

UniProt

O60524

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 881-930 of Human NY-CO-1.

Clonality

Polyclonal

Tissue Specificity

Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875) . May indirectly play a role in nuclear export (PubMed:16103875) .

Molecular Weight

122954 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Nuclear export mediator factor NEMF

Subcellular Location

Nucleus .

Protein Name

Nuclear export mediator factor NEMF

Frequently Asked Questions

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