Anti-TADA2L TADA2A Antibody
Boster Bio Anti-TADA2L TADA2A Antibody catalog # A08832-1. Tested in WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; ADA2-like protein; TADA2A; TADA2L; KL04P;
Gene Name
TADA2A
UniProt
O75478
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 248-293 of Human TADA2L.
Clonality
Polyclonal
Applications
WB, ICC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity) . Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376) . May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376) .
Molecular Weight
51506 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Transcriptional adapter 2-alpha
Subcellular Location
Nucleus
Protein Name
Transcriptional adapter 2-alpha
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