Anti-Complexin-2 CPLX2 Antibody
Boster Bio Anti-Complexin-2 CPLX2 Antibody catalog # A08799. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Complexin-2; Complexin II; CPX II; Synaphin-1; CPLX2;
Gene Name
CPLX2
UniProt
Q6PUV4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human CPLX2.
Clonality
Polyclonal
Tissue Specificity
Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (By similarity) .
Molecular Weight
15394 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Complexin-2
Subcellular Location
Cytoplasm, cytosol. Enriched at synaptic-releasing sites in mature neurons. .
Protein Name
Complexin-2
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