Anti-MED28 Antibody
Boster Bio Anti-MED28 Antibody catalog # A08611-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Mediator of RNA polymerase II transcription subunit 28; Endothelial-derived protein 1; Mediator complex subunit 28; Merlin and Grb2-interacting cytoskeletal protein; Magicin; Tumor angiogenesis marker EG-1; MED28; EG1; FKSG20;
Gene Name
MED28
UniProt
Q9H204
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human MED28
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Highly expressed in vascular tissues such as placenta, testis and liver.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.
Molecular Weight
19520 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Mediator of RNA polymerase II transcription subunit 28
Subcellular Location
Nucleus
Protein Name
Mediator of RNA polymerase II transcription subunit 28
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