Anti-MFNG Antibody
Boster Bio Anti-MFNG Antibody catalog # A08558. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Beta-1,3-N-acetylglucosaminyltransferase manic fringe;2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; MFNG;
Gene Name
MFNG
UniProt
O00587
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 66-110 of Human MFNG
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626) . Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity) .
Molecular Weight
36202 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Beta-1,3-N-acetylglucosaminyltransferase manic fringe
Subcellular Location
Golgi apparatus membrane ; Single-pass type II membrane protein .
Protein Name
Beta-1,3-N-acetylglucosaminyltransferase manic fringe
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