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Anti-MFNG Antibody

Boster Bio Anti-MFNG Antibody catalog # A08558. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Beta-1,3-N-acetylglucosaminyltransferase manic fringe;2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; MFNG;

Gene Name

MFNG

UniProt

O00587

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 66-110 of Human MFNG

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626) . Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity) .

Molecular Weight

36202 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08558

Product MSDS

https://www.bosterbio.com/msds?sku=A08558

Other Gene Names

Beta-1,3-N-acetylglucosaminyltransferase manic fringe

Subcellular Location

Golgi apparatus membrane ; Single-pass type II membrane protein .

Protein Name

Beta-1,3-N-acetylglucosaminyltransferase manic fringe

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