Anti-SMARCD2 Antibody

Boster Bio Anti-SMARCD2 Antibody catalog # A08109. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2;60 kDa BRG-1/Brm-associated factor subunit B; BRG1-associated factor 60B; BAF60B; SMARCD2; BAF60B; PRO2451;

Gene Name

SMARCD2

UniProt

Q92925

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human SMARCD2 (NP_001091896.1) .

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is expressed in the pancreas.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:22952240, PubMed:26601204) . Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation (PubMed:28369036) .