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Anti-PVRL2 NECTIN2 Antibody

Boster Bio Anti-PVRL2 NECTIN2 Antibody catalog # A08081-1. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Nectin-2; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin cell adhesion molecule 2

Gene Name

NECTIN2

UniProt

Q92692

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_002847.1) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705) . Probable cell adhesion protein (PubMed:9657005) .

Molecular Weight

57742 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Nectin-2

Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Name

Nectin-2

Frequently Asked Questions

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