Anti-PVRL2 NECTIN2 Antibody
Boster Bio Anti-PVRL2 NECTIN2 Antibody catalog # A08081-1. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Nectin-2; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin cell adhesion molecule 2
Gene Name
NECTIN2
UniProt
Q92692
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_002847.1) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705) . Probable cell adhesion protein (PubMed:9657005) .
Molecular Weight
57742 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Nectin-2
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Name
Nectin-2
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