Anti-SNRPE Antibody
Boster Bio Anti-SNRPE Antibody catalog # A08077. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Small nuclear ribonucleoprotein E; snRNP-E; Sm protein E; Sm-E; SmE; SNRPE;
Gene Name
SNRPE
UniProt
P62304
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SNRPE (NP_003085.1) .
Clonality
Polyclonal
Tissue Specificity
Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:23246290, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Is also a component of the minor U12 spliceosome (PubMed:15146077) . As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319) . May indirectly play a role in hair development (PubMed:23246290) .
Molecular Weight
10804 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Small nuclear ribonucleoprotein E
Subcellular Location
Cytoplasm, cytosol
Protein Name
Small nuclear ribonucleoprotein E
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
