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Anti-SNRPE Antibody

Boster Bio Anti-SNRPE Antibody catalog # A08077. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Small nuclear ribonucleoprotein E; snRNP-E; Sm protein E; Sm-E; SmE; SNRPE;

Gene Name

SNRPE

UniProt

P62304

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human SNRPE (NP_003085.1) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:23246290, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Is also a component of the minor U12 spliceosome (PubMed:15146077) . As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319) . May indirectly play a role in hair development (PubMed:23246290) .

Molecular Weight

10804 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08077

Product MSDS

https://www.bosterbio.com/msds?sku=A08077

Other Gene Names

Small nuclear ribonucleoprotein E

Subcellular Location

Cytoplasm, cytosol

Protein Name

Small nuclear ribonucleoprotein E

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