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Anti-Filamin-binding LIM protein 1 FBLIM1 Antibody

Boster Bio Anti-Filamin-binding LIM protein 1 FBLIM1 Antibody catalog # A08050. Tested in WB applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Filamin-binding LIM protein 1; FBLP-1; Migfilin; Mitogen-inducible 2-interacting protein; MIG2-interacting protein; FBLIM1; FBLP1;

Gene Name

FBLIM1

UniProt

Q8WUP2

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Recombinant fusion protein of human FBLIM1 (NP_060026.2) .

Clonality

Polyclonal

Tissue Specificity

Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin- containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.

Molecular Weight

40670 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08050

Product MSDS

https://www.bosterbio.com/msds?sku=A08050

Other Gene Names

Filamin-binding LIM protein 1

Subcellular Location

Cell junction, focal adhesion

Protein Name

Filamin-binding LIM protein 1

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