Anti-Filamin-binding LIM protein 1 FBLIM1 Antibody
Boster Bio Anti-Filamin-binding LIM protein 1 FBLIM1 Antibody catalog # A08050. Tested in WB applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Filamin-binding LIM protein 1; FBLP-1; Migfilin; Mitogen-inducible 2-interacting protein; MIG2-interacting protein; FBLIM1; FBLP1;
Gene Name
FBLIM1
UniProt
Q8WUP2
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human FBLIM1 (NP_060026.2) .
Clonality
Polyclonal
Tissue Specificity
Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin- containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Molecular Weight
40670 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Filamin-binding LIM protein 1
Subcellular Location
Cell junction, focal adhesion
Protein Name
Filamin-binding LIM protein 1
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