What is the catalog number for Anti-COPS3 (M408) Antibody?

The catalog number for Anti-COPS3 (M408) Antibody is A07987.

What sizes are available for Anti-COPS3 (M408) Antibody?

Anti-COPS3 (M408) Antibody is available in the following size(s): 100 µL.

Is Anti-COPS3 (M408) Antibody in stock?

Anti-COPS3 (M408) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-COPS3 (M408) Antibody?

The safety data sheet for Anti-COPS3 (M408) Antibody is available here: https://www.bosterbio.com/msds?sku=A07987.

Anti-COPS3 (M408) Antibody

Boster Bio Anti-COPS3 (M408) Antibody catalog # A07987. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

COP9 signalosome complex subunit 3; SGN3; Signalosome subunit 3; JAB1-containing signalosome subunit 3; COPS3; CSN3;

Gene Name

COPS3

UniProt

Q9UNS2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 376-425 of Human COPS3.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. Expressed at high level in heart and skeletal muscle.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.