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Anti-IBTK Antibody

Boster Bio Anti-IBTK Antibody catalog # A07985. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Inhibitor of Bruton tyrosine kinase; IBtk; IBTK; BTKI, KIAA1417;

Gene Name

IBTK

UniProt

Q9P2D0

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein of human IBTK (NP_056340.2) .

Clonality

Polyclonal

Tissue Specificity

Expressed in DeFew, HEK293T, HeLa and in Jurkat, MC3 and NB4 lymphoid cells (at protein level) . Isoform 1 is the predominant isoform expressed in all examined tissues and cell lines. Highly expressed in hemopoietic tissues (fetal liver, spleen, lymph node, thymus, peripheral blood leukocytes and bone marrow) . Weakly or not expressed in other tissues.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.

Molecular Weight

150528 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07985

Product MSDS

https://www.bosterbio.com/msds?sku=A07985

Other Gene Names

Inhibitor of Bruton tyrosine kinase

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Translocates to the plasma membrane upon IgM stimulation.

Protein Name

Inhibitor of Bruton tyrosine kinase

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