Anti-Dok-2 (R293) Antibody
Boster Bio Anti-Dok-2 (R293) Antibody catalog # A07956-1. Tested in IHC, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2) ; DOK2;
Gene Name
DOK2
UniProt
O60496
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 271-320 of Human Dok-2.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver.
Applications
IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity) . .
Molecular Weight
45379 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Docking protein 2
Protein Name
Docking protein 2
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