Anti-TRIAP1 Antibody

Boster Bio Anti-TRIAP1 Antibody catalog # A07930. Tested in WB, IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

TP53-regulated inhibitor of apoptosis 1; Protein 15E1.1; WF-1; p53-inducible cell-survival factor; p53CSV; TRIAP1;15E1.1; HSPC132;

Gene Name

TRIAP1

UniProt

O43715

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human TRIAP1.

Clonality

Polyclonal

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759) . Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602) . Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003) .