Anti-Sestrin-3 SESN3 Antibody
Boster Bio Anti-Sestrin-3 SESN3 Antibody catalog # A07894. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Sestrin-3 ; SESN3
Gene Name
SESN3
UniProt
P58005
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human SESN3 (NP_653266.2) .
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:200-1:2000
Form
Liquid
Function
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562) . May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity) . This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity) .
Molecular Weight
57291 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Sestrin-3
Subcellular Location
Cytoplasm
Protein Name
Sestrin-3
Curated Selection
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