Anti-HLA-DOB Antibody
Boster Bio Anti-HLA-DOB Antibody catalog # A07815-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
HLA class II histocompatibility antigen, DO beta chain; MHC class II antigen DOB; HLA-DOB;
Gene Name
HLA-DOB
UniProt
P13765
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the 43-88 of Human HLA-DOB.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Molecular Weight
30822 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
HLA class II histocompatibility antigen, DO beta chain
Subcellular Location
Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
Protein Name
HLA class II histocompatibility antigen, DO beta chain
Curated Selection
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