Anti-ASC-1 TRIP4 Antibody
Boster Bio Anti-ASC-1 TRIP4 Antibody catalog # A07762-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Activating signal cointegrator 1
Gene Name
TRIP4
UniProt
Q15650
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human TRIP4 (NP_057297.2) .
Clonality
Polyclonal
Applications
WB, IHC, IP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498) . Also involved in androgen receptor transactivation (By similarity) . Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347) . May play a role in the development of neuromuscular junction (PubMed:26924529) . May play a role in late myogenic differentiation (By similarity) .
Molecular Weight
66146 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Activating signal cointegrator 1
Subcellular Location
Nucleus
Protein Name
Activating signal cointegrator 1
Curated Selection
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