Anti-VIPAS39 Antibody

Boster Bio Anti-VIPAS39 Antibody catalog # A07696. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Spermatogenesis-defective protein 39 homolog; hSPE-39; VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein in polarity and apical restriction; VIPAS39; C14orf133, SPE39, VIPAR;

Gene Name

VIPAS39

UniProt

Q9H9C1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human VIPAS39 (NP_071350.2) .

Clonality

Polyclonal

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A- dependent recycling pathway and in the maintenance of the apical- basolateral polarity (PubMed:20190753) . May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of VPS33B (PubMed:19109425) . May play a role in vesicular trafficking during spermatogenesis (By similarity) . May be involved in direct or indirect transcriptional regulation of E- cadherin (By similarity) .