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Anti-EDF1 Antibody

Boster Bio Anti-EDF1 Antibody catalog # A07668. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Endothelial differentiation-related factor 1; EDF-1; Multiprotein-bridging factor 1; MBF1; EDF1;

Gene Name

EDF1

UniProt

O60869

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human EDF1 (NP_003783.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed in brain, liver, lung, kidney and heart (at protein level) . Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.

Molecular Weight

16369 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07668

Product MSDS

https://www.bosterbio.com/msds?sku=A07668

Other Gene Names

Endothelial differentiation-related factor 1

Subcellular Location

Cytoplasm. Nucleus. Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.

Protein Name

Endothelial differentiation-related factor 1

Curated Selection

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