Anti-EDF1 Antibody
Boster Bio Anti-EDF1 Antibody catalog # A07668. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Endothelial differentiation-related factor 1; EDF-1; Multiprotein-bridging factor 1; MBF1; EDF1;
Gene Name
EDF1
UniProt
O60869
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human EDF1 (NP_003783.1) .
Clonality
Polyclonal
Tissue Specificity
Expressed in brain, liver, lung, kidney and heart (at protein level) . Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
Molecular Weight
16369 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Endothelial differentiation-related factor 1
Subcellular Location
Cytoplasm. Nucleus. Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Protein Name
Endothelial differentiation-related factor 1
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