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Anti-Netrin receptor UNC5A UNC5A Antibody

Boster Bio Anti-Netrin receptor UNC5A UNC5A Antibody catalog # A07537. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Netrin receptor UNC5A; Protein unc-5 homolog 1; Protein unc-5 homolog A; UNC5A; KIAA1976, UNC5H1;

Gene Name

UNC5A

UniProt

Q6ZN44

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human UNC5A

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:1000

Form

Liquid

Function

Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

Molecular Weight

92932 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Netrin receptor UNC5A

Subcellular Location

Cell membrane

Protein Name

Netrin receptor UNC5A

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