Anti-Synuclein-Beta (S118) SNCB Antibody
Boster Bio Anti-Synuclein-Beta (S118) SNCB Antibody catalog # A07381S118. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Beta-synuclein; SNCB;
Gene Name
SNCB
UniProt
Q16143
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 82-140 of Human Synuclein-β.
Clonality
Polyclonal
Tissue Specificity
Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA) -stimulated caspase activation in a p53/TP53- dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Molecular Weight
14288 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Beta-synuclein
Subcellular Location
Cytoplasm.
Protein Name
Beta-synuclein
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