Anti-Mucin-20 MUC20 Antibody
Boster Bio Anti-Mucin-20 MUC20 Antibody catalog # A07372-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Mucin-20; MUC-20; MUC20; KIAA1359; UNQ2782/PRO7170;
Gene Name
MUC20
UniProt
Q8N307
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human MUC20.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Form
Liquid
Function
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF) -induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Molecular Weight
71982 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Mucin-20
Subcellular Location
Secreted . Apical cell membrane
Protein Name
Mucin-20
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