Anti-CBR4 Antibody
Boster Bio Anti-CBR4 Antibody catalog # A07359. Tested in WB applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Carbonyl reductase family member 4;1.-.-.-
Gene Name
CBR4
UniProt
Q8N4T8
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human CBR4 (NP_116172.2) .
Clonality
Polyclonal
Tissue Specificity
Detected in liver and kidney (at protein level) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:200-1:2000
Form
Liquid
Function
The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508) . Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508) . The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905) . Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10- phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508) .
Molecular Weight
25301 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Carbonyl reductase family member 4
Subcellular Location
Mitochondrion matrix
Protein Name
Carbonyl reductase family member 4
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