Anti-UACA Antibody
Boster Bio Anti-UACA Antibody catalog # A07252. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Uveal autoantigen with coiled-coil domains and ankyrin repeats; UACA; KIAA1561;
Gene Name
UACA
UniProt
Q9BZF9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human UACA
Clonality
Polyclonal
Tissue Specificity
Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes. Expressed in eye muscles and thyroid follicular cells.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) . .
Molecular Weight
162505 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Subcellular Location
Nucleus
Protein Name
Uveal autoantigen with coiled-coil domains and ankyrin repeats
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