Anti-NUP85 Antibody
Boster Bio Anti-NUP85 Antibody catalog # A07147. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Nuclear pore complex protein Nup85;85 kDa nucleoporin; FROUNT; Nucleoporin Nup75; Nucleoporin Nup85; Pericentrin-1; NUP85; NUP75, PCNT1;
Gene Name
NUP85
UniProt
Q9BW27
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human NUP85 (NP_079120.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (PubMed:12718872) . As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus (PubMed:12718872) . The Nup107-160 complex seems to be required for spindle assembly during mitosis (PubMed:16807356) . NUP85 is required for membrane clustering of CCL2-activated CCR2 (PubMed:15995708) . Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade (PubMed:15995708) .
Molecular Weight
75019 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Nuclear pore complex protein Nup85
Subcellular Location
Nucleus, nuclear pore complex
Protein Name
Nuclear pore complex protein Nup85
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