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Anti-Nephrocystin-5 (R467) IQCB1 Antibody

Boster Bio Anti-Nephrocystin-5 (R467) IQCB1 Antibody catalog # A07108-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

IQ calmodulin-binding motif-containing protein 1; Nephrocystin-5; p53 and DNA damage-regulated IQ motif protein; PIQ; IQCB1; KIAA0036, NPHP5; OK/SW-cl.85;

Gene Name

IQCB1

UniProt

Q15051

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 432-486 of Human Nephrocystin-5.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (PubMed:21565611, PubMed:23446637) . Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (PubMed:25552655) .

Molecular Weight

68929 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07108-1

Product MSDS

https://www.bosterbio.com/msds?sku=A07108-1

Other Gene Names

IQ calmodulin-binding motif-containing protein 1

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Protein Name

IQ calmodulin-binding motif-containing protein 1

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