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Anti-GCC2 Antibody

Anti-GCC2 Antibody tested in WB, reactive to human

Product Specifications

Synonyms

GRIP and coiled-coil domain-containing protein 2;185 kDa Golgi coiled-coil protein; GCC185; CLL-associated antigen KW-11; CTCL tumor antigen se1-1; Ran-binding protein 2-like 4; RanBP2L4; Renal carcinoma antigen NY-REN-53; GCC2; KIAA0336, RANBP2L4;

Gene Name

GCC2

UniProt

Q8IWJ2

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GCC2

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB

Field of Research

G Protein Signaling, Golgi Proteins, Protein Trafficking, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Vesicle Transport

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Function

Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.

Molecular Weight

195910 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07107-1

Product MSDS

https://www.bosterbio.com/msds?sku=A07107-1

Other Gene Names

GRIP and coiled-coil domain-containing protein 2

Subcellular Location

Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.

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